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. 2018 Mar 9;67(9):274–278. doi: 10.15585/mmwr.mm6709a3

Figure 2.

The figure above is a combination bar chart and line graph showing the number and cumulative number of surgical procedures linked to cases of dura mater graft-associated Creutzfeldt-Jakob disease, by year of surgical procedure, in Japan during 1975–1993.

Number of surgical procedures linked to cases of dura mater graft-associated Creutzfeldt-Jakob disease (dCJD),* by year of surgical procedure — Japan, 1975–1993

* Among 154 dura mater graft procedures, the brand was documented as Lyodura in 140 (91%).

The manufacturer of Lyodura reported that it revised its collection and processing procedures in May 1987 to reduce the risk for CJD contamination; the recommended shelf life for Lyodura was 5 years.