Table 1. GO terms enriched in genes differentially expressed in tame vs. aggressive pituitary tissues at FDR < 0.01.
Group | GO ID | Term Description | Adjusted P-Value | DEG Annotated with this Term | % Genes in this Term Differentially Expressed |
---|---|---|---|---|---|
1 | GO:0031268 | Pseudopodium organization | 0.007 | CDC42EP2, SRGAP2, SRGAP3, WASH1 | 28.6 |
2 | GO:0007259 | JAK-STAT cascade | 0.007 | ASPN, CISH, ERBB4, FLRT1, FLRT3, IL6ST, LRRC4B, PTGER4, SOCS2, STAT3a, TNFRFSF1A | 8.3 |
GO:0097696 | STAT cascade | 0.007 | 8.3 | ||
GO:0046425 | Regulation of JAK-STAT cascade | 0.009 | 9.2 | ||
GO:1904892 | Regulation of STAT cascade | 0.009 | 9.2 | ||
3 | GO:2001198 | Regulation of dendritic cell differentiation | 0.008 | LGALS3, LGALS9, TMEM176b | 50 |
4 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 0.008 | RPL17, RPL23A, RPL26, RPL4, RPL7A, RPS24, RPS3A, ZFAND2Bb | 10.7 |
GO:0006613 | Cotranslational protein targeting to membrane | 0.008 | 10.5 | ||
GO:0045047 | Protein targeting to ER | 0.008 | 10.4 | ||
GO:0016259 | Selenocysteine metabolic process | 0.009 | 11.7 | ||
5 | GO:0071621 | Granulocyte chemotaxis | 0.010 | IL17RA, IL17RC, ITGA1, LGALS3, NCKAP1L, PDE4B, TGFB2, THBS4, VAV3 | 10.1 |
STAT3 is not associated with GO:1904892.
ZFAND2B is not associated with GO:0016259.