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. 2018 Jan 29;8(3):859–873. doi: 10.1534/g3.117.300508

Table 1. GO terms enriched in genes differentially expressed in tame vs. aggressive pituitary tissues at FDR < 0.01.

Group GO ID Term Description Adjusted P-Value DEG Annotated with this Term % Genes in this Term Differentially Expressed
1 GO:0031268 Pseudopodium organization 0.007 CDC42EP2, SRGAP2, SRGAP3, WASH1 28.6
2 GO:0007259 JAK-STAT cascade 0.007 ASPN, CISH, ERBB4, FLRT1, FLRT3, IL6ST, LRRC4B, PTGER4, SOCS2, STAT3a, TNFRFSF1A 8.3
GO:0097696 STAT cascade 0.007 8.3
GO:0046425 Regulation of JAK-STAT cascade 0.009 9.2
GO:1904892 Regulation of STAT cascade 0.009 9.2
3 GO:2001198 Regulation of dendritic cell differentiation 0.008 LGALS3, LGALS9, TMEM176b 50
4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 0.008 RPL17, RPL23A, RPL26, RPL4, RPL7A, RPS24, RPS3A, ZFAND2Bb 10.7
GO:0006613 Cotranslational protein targeting to membrane 0.008 10.5
GO:0045047 Protein targeting to ER 0.008 10.4
GO:0016259 Selenocysteine metabolic process 0.009 11.7
5 GO:0071621 Granulocyte chemotaxis 0.010 IL17RA, IL17RC, ITGA1, LGALS3, NCKAP1L, PDE4B, TGFB2, THBS4, VAV3 10.1
a

STAT3 is not associated with GO:1904892.

b

ZFAND2B is not associated with GO:0016259.