Table 4. Neurons in which daf-19 controls target gene expression.
| Neuron | Target genes | Selected neuron functions |
|---|---|---|
| IL2s | asic-2, spg-20, ddn-1 | Dauer behavior |
| URX | ddn-1 | Suppresses innate immunity, life span regulation |
| ASK | ddn-1 | Initiates local search behavior |
| AFD | ddn-1 | Ablation causes hypo-reversal |
| ASG | ddn-1, eppl-1, del-4 | Inhibits entry into dauer |
| ASI | ddn-1 | Suppresses turning, promotes dispersal, modulates innate immune response |
| ASE | del-4, eppl-1, ddn-1 | Food leaving behavior |
| AIY | del-4 | Suppresses turns and reversals, regulates life span, starvation response |
| I5 | ddn-1 | Regulates pharyngeal muscle relaxation |
| M5 | ddn-1 | Unknown |
| PHA, PHB | mapk-15 | Chemorepulsion, mate searching |
| IL1s | skr-12, mapk-15 | Spontaneous and faster foraging |
| OLQs | skr-12 | Spontaneous and faster foraging |
| BAG | gakh-1 | Controls life span, food leaving behavior |
| AFD | skr-12 | Ablation causes hypo-reversal |
| ADF | skr-12 | Inhibits entry into dauer, modulates NMJ transmission |
| ASG | skr-12 | Inhibits entry into dauer |
| I2 | rgs-8.1 | Unknown function |
| RID | rgs-8.1 | Unknown function |
| AVA | gakh-1 | Driver for backward locomotion |
| AVB | gakh-1 | Driver for forward locomotion |
| SIAD/V | gakh-1 | Nerve ring placement |
| AIN | gakh-1 | Unknown function |
| M4 | gakh-1 | Posterior isthmus peristalsis |
Neurons in which daf-19 presence activates or represses target gene expression, and associated neuron functions [from Altun et al. (2002–2017)] relevant to daf-19 mutant phenotypes. Neurons are listed top to bottom by their position in the worm, anterior to posterior. Ciliated sensory neurons are in bold. NMJ, neuromuscular junction.