Table 1. Genes involved in pairing and synapsis.
Gene symbol | Common name (homolog) | Functiona | References |
---|---|---|---|
klaroid | SUN domain protein | Inner nuclear membrane protein | Christophorou et al. (2015) |
klarsicht | KASH domain | Outer nuclear member protein | Christophorou et al. (2015) |
dhc | Dynein heavy chain | Minus-end-directed motor | Christophorou et al. (2015) |
Chromosome axis | |||
smc1 | Smc1 | Core cohesion component | Khetani and Bickel (2007); Gyuricza et al. (2016) |
smc3 | Smc3 | Core cohesion component | Khetani and Bickel (2007); Gyuricza et al. (2016) |
ord | Cohesion: Ord complex | Bickel et al. (1996), (2002); Gyuricza et al. (2016) | |
sunn | Stromalin-related | Cohesion: Ord complex | Krishnan et al. (2014); Gyuricza et al. (2016) |
solo | Cohesion: Ord complex | Yan and McKee (2013); Gyuricza et al. (2016) | |
SA | Stromalin | Cohesion: C(2)M complex | Gyuricza et al. (2016) |
NipB | SCC2 | Cohesion: C(2)M complex | Gyuricza et al. (2016) |
rad21/vtd | SCC1 | Cohesion | Urban et al. (2014) |
SC lateral element | |||
c(2)M | Kleisin-like protein; cohesion: C(2)M complex | Manheim and McKim (2003); Heidmann et al. (2004); Gyuricza et al. (2016); Cahoon et al. (2017) | |
SC central region | |||
c(3)G | Zip1/SCP1 | Transverse filament | Hall (1972); Page and Hawley (2001); Cahoon et al. (2017) |
corolla | Transverse filament-like protein | Collins et al. (2014); Cahoon et al. (2017) | |
cona | Central element | Page et al. (2008); Lake and Hawley (2012); Cahoon et al. (2017) |
SUN, Sad1p, UNC-84; KASH, Klarsicht, ANC-1, Syne homology; SC, synaptonemal complex.
Most likely function based on genetic, biochemical, or cytological data.