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An example of a replication assay performed with replicon RNA transfection. The control sample (RenR) shows normal high level of replication; the sample incubated in the presence of 2mM guanidine-HCl (RenR+Gua) reflects translation of the input RNA. The data show average luciferase signal from 16 wells of a 96-well plate, bars represent standard deviation. The data were processed by GraphPad Prizm software.
