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Baseline characteristics: subgroups according to Crea-Cl (median; range)
| Crea-Cl <125 mL/min n=36 |
Crea-Cl >125 mL/min No dose capping, n=29 |
||
| Age (years) | 47 (22–71) | 33 (23–53) | P=0.0001 |
| SCr (μmol/L) | 79 (51–117) | 77 (52–92) | NS |
| Crea-Cl (mL/min) | 109 (70–120)* | 143 (125–184)* | |
| Carboplatin dose (g) | 950 (700–1020)* | 1200 (1050–1480)* |
*Significant differences due to definition of subgroup.
Crea-Cl, creatinine-clearance; SCr, serum-creatinine.
