Table 3.

Adverse events of grade 3 or higher

	Cytotoxic drugs only (n=31)	Molecular targeted drugs only (n=21)	Cytotoxic and molecular targeted drugs (n=3)	Total (N=55)
Neutropaenia	5 (16%)	1 (5%)	1 (33%)	7 (13%)
Leucocytopaenia	3 (10%)	1 (5%)	1 (33%)	5 (9%)
Anaemia	5 (16%)	3 (14%)	1 (33%)	9 (16%)
Thrombocytopaenia	3 (10%)	3 (14%)		6 (11%)
Febrile neutropaenia	1 (3%)			1 (2%)
Nausea	1 (3%)			1 (2%)
Anorexia	1 (3%)		1 (33%)	2 (4%)
Diarrhoea	1 (3%)			1 (2%)
Small intestinal mucositis	1 (3%)			1 (2%)
Enterocolitis infection	1 (3%)			1 (2%)
Colonic haemorrhage	1 (3%)			1 (2%)
Rectal ulcer	1 (3%)			1 (2%)
Skin-related toxicities			1 (33%)	1 (2%)
Peripheral sensory neuropathy			1 (33%)	1 (2%)
Stroke		1 (5%)		1 (2%)
Pneumonitis	1 (3%)	2 (10%)		3 (5%)
Sepsis	1 (3%)			1 (2%)