Table 1.
Number and Percentage Distribution of Demographic and Clinical Characteristics among non-Hispanic black and white Males (N = 21,524), by HPV Status National Cancer Database, 2009–2013.
| Characteristic | Total n = 21,524 |
HPV+ n = 8418 (39%) |
HPV− n = 13,106 (61%) |
P |
|---|---|---|---|---|
| Age, mean years [SD] | 59.9 (10.6) | 58.1 (9.1) | 61.1 (11.3) | <0.0001 |
| Race | ||||
| Non-Hispanic white | 19,428 (90) | 7993 (95) | 11,435 (87) | <0.0001 |
| Non-Hispanic black | 2096 (10) | 425 (5) | 1671 (13) | |
| Age Group | ||||
| <40 | 459 (2) | 135 (2) | 324 (3) | <0.0001 |
| 40–49 | 2698 (13) | 1248 (15) | 1450 (11) | |
| 50–59 | 7803 (36) | 3487 (41) | 4316 (33) | |
| 60–69 | 6825 (32) | 2710 (32) | 4115 (31) | |
| 70–79 | 2777 (13) | 700 (8) | 2077 (16) | |
| 80+ | 962 (4) | 138 (2) | 824 (6) | |
| Charlson/Deyo comorbidity scorea | ||||
| 0 | 17104 (80) | 7029 (84) | 10075 (77) | <0.0001 |
| 1 | 3435 (16) | 1115 (13) | 2320 (18) | |
| 2 | 985 (4) | 274 (3) | 711 (5) | |
| Primary payer at diagnosis | ||||
| Not insured | 1242 (6) | 391 (5) | 851 (7) | <0.0001 |
| Private insurance | 10626 (49) | 5201 (62) | 5425 (41) | |
| Medicaid | 2058 (10) | 539 (6) | 1519 (12) | |
| Medicare | 6818 (32) | 1998 (24) | 4820 (37) | |
| Other government | 478 (2) | 209 (2) | 269 (2) | |
| Insurance status unknown | 302 (1) | 80 (1) | 222 (2) | |
| Socioeconomic status (area-level) tertilesb | ||||
| 1st Tertile (Lowest) | 7025 (33) | 2200 (26) | 4825 (37) | <0.0001 |
| 2nd | 6934 (32) | 2763 (33) | 4171 (32) | |
| 3rd Tertile (Highest) | 7473 (35) | 3419 (44) | 4054 (31) | |
| Missing | 92 | 36 | 56 | |
| Rural–Urban continuum, 2003c | ||||
| Rurald | 1095 (5) | 467 (6) | 628 (5) | 0.014 |
| Urbane | 19913 (95) | 7752 (94) | 12161 (95) | |
| Missing | 516 | 199 | 317 | |
| Anatomical site | ||||
| Lip | 244 (1) | 13 (<1) | 231 (2) | <0.0001 |
| Tongue (anterior) | 1801 (9) | 248 (3) | 1553 (12) | |
| Gum, Front of Mouth, Other Mouth | 1951 (9) | 224 (3) | 1727 (13) | |
| Tongue (base) | 4604 (21) | 2840 (34) | 1764 (13) | |
| Tonsil | 5896 (27) | 3896 (46) | 2000 (15) | |
| Oropharynx | 1058 (5) | 444 (5) | 614 (5) | |
| Nasopharynx | 506 (2) | 138 (2) | 368 (3) | |
| Hypopharynx | 977 (5) | 146 (2) | 831 (6) | |
| Other pharynx | 311 (1) | 108 (1) | 203 (2) | |
| Larynx | 4176 (19) | 361 (4) | 3815 (29) | |
| HNSCC site group | ||||
| Oral Cavityf | 3996 (18) | 485 (6) | 3511 (27) | <0.0001 |
| Oropharyngealg | 11558 (54) | 7180 (85) | 4378 (33) | |
| Non-Oropharyngeal/laryngealh | 5970 (28) | 753 (9) | 5217 (40) | |
| Year of diagnosis | ||||
| 2009 | 130 (1) | 38 (<1) | 92 (<1) | <0.0001 |
| 2010 | 2672 (12) | 949 (11) | 1723 (13) | |
| 2011 | 4968 (23) | 1746 (21) | 3222 (25) | |
| 2012 | 6316 (29) | 2519 (30) | 3797 (29) | |
| 2013 | 7438 (35) | 3166 (38) | 4272 (33) |
Charlson/Deyo Score with values 0 (no comorbid conditions recorded), 1 and 2 (greater than 1).
Area-level composite measure of SES divided into thirds at the tertiles of the sample distribution.
Area-based measure of rurality and urban influence estimated by matching the state and county FIPS code of the patient recorded at the time of diagnosis against the 2013 typology published by the United States Department of Agriculture Economic Research Service.
Rural designation includes: Urban population of ≥ 20000 and not adjacent to a metro area, or completely rural/<2500 urban population and adjacent to a metro area, or completely rural/<2500 urban population and not adjacent to a metro area.
Urban designation includes: Counties in metro areas of ≥1 million population, or counties in metro areas of 250,000–1 million, or counties in metro areas of <250,000, or urban population of ≥20,000 and adjacent to a metro area, or urban population of 2500–19,999 and adjacent to a metro area, or completely rural/<2500 urban population and adjacent to a metro area.
Oral cavity includes lip, anterior tongue, gum, front of mouth, and other mouth.
Oropharyngeal includes base of tongue, tonsil oropharynx.
Non-oropharyngeal/laryngeal includes nasopharynx, hypopharynx, other pharynx, larynx.