Table 2. Proportional Hazards Cox Regression Model Predicting the Likelihood of Ischemic Cardiovascular Disease by Des-gamma carboxy Prothrombin.

		DCP (quartiles)
	Events/N	Q1 (0.33-2.40)	Q2 (2.41-3.47)	Q3 (3.48-4.63)	Q4 (4.64-<20.1)	DCP (continuous)
Model 1	75/709	reference	1.38	1.83	1.71	1.46
			(0.62-3.06)	(0.81-4.12)	(0.79-3.70)	(1.08-1.97)
			p=0.428	p=0.143	p=0.173	p=0.013
Model 2	74/694	reference	1.48	1.96	2.03	1.58
			(0.62-3.52)	(0.83-4.66)	(0.82-5.04)	(1.13-2.22)
			p=0.378	p=0.126	p=0.125	0.008
Model 3	59/617	reference	1.46	1.82	1.87	1.53
			(0.61-3.50)	(0.78-4.23)	(0.76-4.58)	(1.09-2.13)
			p=0.39	p=0.163	p=0.171	0.013

Abbreviation: DCP = des-gamma carboxy Prothrombin; Q = quartile.

Note: Table shows hazard ratio (95% confidence interval). All models are weighted for case-cohort design and use robust standard errors. Model 1: Adjusted for age, gender, and race/ethnicity. Model 2: Adjusted for Model 1 + BMI, cigarette smoking (never, former, current), education (high school graduate), diabetes, systolic blood pressure, antihypertension medication use, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, high-sensitivity C-reactive protein, lipid-lowering medication, estimated glomular filtration rate, albumin and creatinine ratio, intentional physical activity, and current alcohol use. Model 3: Adjusted for Model 2 + phylloquinone, and dihydrophylloquinone.