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. 2018 Mar 9;15(3):e1002522. doi: 10.1371/journal.pmed.1002522

Fig 2. Changes in plasma hemoglobin, heme, and non-transferrin-bound iron (NTBI) after trauma hemorrhage (TH) and resuscitation with stored blood.

Fig 2

At various times after TH and resuscitation with fresh (day 0) or stored (day 14) red blood cells (RBCs), mouse plasma was collected and free hemoglobin (A), heme (B), and NTBI (C) measured. Each symbol represents an individual sample. Data are mean ± SEM; *p < 0.001 relative to fresh RBCs at 4 h. #p < 0.001 and ##p = 0.02 relative to stored RBCs at 4 h by 2-way ANOVA with Tukey post-test. $p = 0.034 by unpaired t test relative to stored RBCs at 4 h.