Fig. 4.

Using receiver-operating characteristic curves, we assessed multimetabolite biomarker models that could accurately predict a discordant response to HIV-infection treatment.

Model A inputs: large HDL particles, LDL particle size, total particles/HDL particles, LDL particles/HDL particles, glucose, medium VLDL particles and non-HDL particles. For Model B, we used the same metabolomic inputs but the model was adjusted for age and baseline CD4⁺ T-cell count. LDL, low density lipoprotein; HDL, high density lipoprotein; VLDL, very-low-density lipoprotein.