Table 1.

MMP (Rhodamin123 Fluorescence) and ROS Levels in HT-29 and SW948. After cells treatment the observation in 528 nm wavelength were measured. The mean of three independent experiments is shown.*significantly different from control (**P<0.01), ≠ significantly different from Doxorubicin (≠ P<0.05), ¥ significantly different from eupatorin (¥P<0.05) and ψ significantly different from salvigenin (ψP<0.05).

Treatment	MMP (rhodamin123 fluorescence at 528 nm) HT-29 and SW948 cell line respectively	ROS (absorbance at 528 nm) HT-29 and Sw948 cell line respectively
Control	459.54 ±4.27, 558.54±3.41	402.33±3.53, 168.44±3.42
Eupatorin 100µM	768.54±3.62, 749.54±4.98 ** **	734.32±3.36, 424.65±2.45 ** **
salvigenin 150µM	714.66±3.55, 788.54±2.2 ** **	647.25 ±4.24, 401.11±3.23 ** **
Dox 10 µM	891.86±3.22, 942.64±4.3 ** **	802.32±3.86, 551.23±4.65 ** **
Dox 1µM+ Eupatorin 100µM	802.32±2.44, 823.45±3.2 ** ** ¥ ¥	782.34±2.54, 476.23±4.87 ** ** ≠ ≠
Dox 1µM+ salvigenin 150µM	796.43±2.42, 823.48±2.7 ** ** Ψ Ψ	717.74±54, 437.64±4.6 ** ** ≠ ≠