Table 2.
Genotypes and Minor Allele Frequencies among Recruited ALL Patients
| rs | Variant | Genotype / Allele | Observed frequency N(%) | Expected frequency* N(%) | P- value | MAF (%) |
|---|---|---|---|---|---|---|
| rs1800460 | (*3B) c.460G > A | GG | 51 (98.08%) | 51 (98.08%) | 0.99 | 1.00% |
| GA | 1 (1.92 %) | 1 (1.92 %) | ||||
| AA | 0 (0.0 %) | 0 (0.0 %) | ||||
| rs1142345 | (*3C) c.719A > G | AA | 47 (98%) | 47 (98%) | 0.99 | 1.00% |
| AG | 1 (2%) | 1 (2%) | ||||
| GG | 0 (0.0%) | 0 (0.0%) | ||||
| rs1800462 | (*2) c.238G>C | GG | 51 (100%) | 51 (100%) | 1 | 0.00% |
| GC | 0 (0.0%) | 0 (0.00%) | ||||
| CC | 0 (0.0%) | 0 (0.00%) | ||||
| rs1800460 & rs1142345 | TPMT*3A (c.460G>A and c.719A>G) | Carriers of both TPMT*3B and TPMT*3C alleles | 0 (0.0%) | 0 (0.00%) | - | - |
*
, Using Hardy-Weinberg Equilibrium; MAF, minor allele frequency; N, numbe; %, percentage