Table 2.
Biochemical Failure Free Progression at 3, 5 and 10 Years. Comparing observed survival (Kaplan-Meier) versus predicted (Model FP) versus in 321 men treated by radical prostatectomy
| Group | Survival to 3 years Percentage v (CI:95%) | Survival to 5 years Percentage (CI:95%) | Survival to 10 years Percentage (CI:95%) | |||
|---|---|---|---|---|---|---|
| Observed a | Predicted b | Observed a | Predicted b | Observed a | Predicted b | |
| A | 99.29% | 98.57 | 94.69 | 96.06 | 92.7 | 82.52% |
| (95.04 to 99.90) | (96.23 to 99.46) | (89.18 to 97.44) | (92.87 to 97.84) | (86.34 to 96.16) | (74.33 to 88.30) | |
| B | 98.15 | 98.57 | 98.15 | 94.21 | 55.83 | 75.15% |
| (87.57 to 99.74) | (95.74 to 99.53) | (87.57 to 99.74) | (89.36 to 96.90) | (37.17 to 70.94) | (63.44 to 83.58) | |
| C | 46.15% | 56.76% | 41.03% | 38.26% | 6.41% | 10.63% |
| (30.16 to 60.73) | (44.23 to 67.49) | (25.69 to 55.76) | (25.68 to 50.70) | (1.19 to 18.21) | (3.80 to 21.53) | |
| D | 48.86% | 43.02% | 26.14 | 24.39 | 4.96% | 3.57% |
| (38.09 to 58.78) | (34.06 to 51.66) | (17.49 to 35.60) | (16.95 to 32.57) | (1.64 to 11.13) | (1.30 to 7.74) | |
a
Observed survival, Kaplan-Meier Survival;
b
Predicted Survival Model FP, indicates flexible parametric survival final model on scale hazard; incorporates the presence of CPC and mM, with four degrees of freedom for baseline hazard function (DF4) and CPC as variable time-dependent effect (TVC) with one degrees of freedom (DFTVC1).