Table 5.
Predictors of Each FACT-Hep Dimension among Hepatocellular Carcinoma Patients after Surgical Resection During the Study Perioda
| Predictorsb | Physical well-being | Social/ Family well-being | Emotional well-being | Functional well-being | Additional concerns for HCC | Trial outcome index | FACT-G total | FACT-Hep total |
|---|---|---|---|---|---|---|---|---|
| Gender | ||||||||
| Male | 0.87* | -0.02 | 0.31 | 1.41 | 1.78** | 3.67** | 1.48 | 3.07** |
| Age, years | -0.10*** | -0.08 | -0.13*** | -0.09** | -0.16*** | -0.28*** | -0.27*** | -0.36*** |
| Education | ||||||||
| Primary school | 2.32* | -2.85 | 2.22** | 1.88 | 4.13** | 6.67*** | 4.62** | 7.08** |
| Junior high school | 2.41** | -0.25 | 3.70*** | 3.25** | 4.81*** | 8.30*** | 8.67*** | 11.22*** |
| Senior high school | 2.52*** | 2.17 | 3.46*** | 2.93** | 3.92*** | 7.01*** | 8.25*** | 9.69*** |
| College and above | 4.57*** | -1.01 | 5.05*** | 5.09*** | 7.67*** | 14.94*** | 13.95*** | 18.95*** |
| Marital status | ||||||||
| Married or living with partner | 0.58 | 4.83* | 1.38 | 1.49 | 0.66 | 2.69 | 5.76 | 6.12 |
| BMI , kg/m2 | ||||||||
| Overweight | 0.33 | 0.15 | 0.52 | 0.7 | -0.01 | 0.54 | 1.71 | 1.33 |
| Obese | 0.42 | -3.64 | 0.73 | 0.85 | -0.67 | 0.26 | 1.81 | 0.97 |
| Co-residence with family | ||||||||
| Yes | 1.75 | 5.46** | 3.83** | 0.09 | 5.92** | 5.06** | 3.09 | 6.52** |
| Smoking | ||||||||
| Yes | 0.27 | 0.9 | 0.71 | -2.04** | 0.23 | 2.66 | 3 | 3.29 |
| Drinking | ||||||||
| Yes | 0.14 | -0.53 | 0.12 | -0.38 | 1.14 | 0.83 | 0.43 | 1.48 |
| Tumor stage | ||||||||
| II | 0.14 | -2.31 | 0.08 | 0.44 | -0.84 | -0.29 | 0.93 | -0.02 |
| III | 0.24 | -3.33 | 0.15 | 0.1 | -0.27 | 0 | -1.45 | -2.05 |
| Chemotherapy | ||||||||
| Yes | 1.8 | 1.18 | 1.25 | -0.21 | 1.17 | 2.68 | 4.78 | 5.95 |
| Radiotherapy | ||||||||
| Yes | 0.56 | 7.33 | 1.22 | 4.83 | 0.53 | 6.05 | 9.42 | 9.7 |
| ALOS, days | -0.06** | -0.01 | 0.01 | -0.08** | -0.04 | -0.20** | -0.16** | -0.22** |
| HRQoL, pre-operative score | 0.57*** | 0.65*** | 0.27*** | 0.51*** | 0.68*** | 0.70*** | 0.65*** | 0.73*** |
a
Values are expressed as the coefficient from the generalized estimating equation model;
b
References: gender (female), education (no formal education), marital status (divorced or widowed), BMI (normal), co-residence with family (no), smoking (no), drinking (no), tumor stage (I), chemotherapy (no), radiotherapy (no). FACT-Hep, Functional Assessment of Cancer Therapy - Hepatobiliary; FACT-G, Functional Assessment of Cancer Therapy - General; BMI, body mass index; ALOS, average length of stay; HRQoL, health-related quality of life;
*
p<0.05;
**
p<0.01;
***
p<0.001