Author response image 2. Compared phenotypes resulting from the overexpression of Hh^C85S and N- terminally truncated variants in the Hh-producing and Hh-receiving compartments of the wing disc.

(A-F) Adult wing structures as a result of ptc-Gal4-mediated overexpression of non- palmitoylated Hh in wild type background (at 25 °C). Note that proximal L3-L4 intervein spaces get slightly reduced (B-D) and, in addition, varying numbers of wings lacked the ACV (E and Table 1 below). Wing patterning is fully restored upon deletion of the most N-terminal 15 amino acids.