Table 3. List of up-regulated and down-regulated miRNAs detected using small RNA-seq (FC ≥ 2.83, P < 0.05).

miR_name	fold-change(log2 Tum/Ctr)	up-or-down	p_value	sig-lable
hsa-miR-9-3p	–7.10538475	down	0.000122742	**
hsa-miR-1303	–6.86430997	down	0.000490585	**
hsa-miR-223-3p	–3.53749571	down	1.65E-266	**
hsa-miR-509-3-5p	–3.49076386	down	4.54E-10	**
hsa-miR-509-5p	–2.50137905	down	0.00149862	**
hsa-miR-450a-2-3p	–2.22132264	down	0.007574552	**
hsa-miR-337-5p	–2.13638952	down	0.000918863	**
hsa-miR-135a-5p	–2.11442989	down	0.012782924	*
hsa-miR-513c-5p	–2.11442989	down	0.012782924	*
hsa-miR-2355-3p	–2.08634155	down	0.004368201	**
hsa-miR-202-5p	–1.99889374	down	0.007235532	**
hsa-miR-200c-5p	–1.99886536	down	0.021358055	*
hsa-miR-664b-3p	–1.99886536	down	0.021358055	*
hsa-miR-3648	–1.93753391	down	0.001441353	**
hsa-miR-429	–1.93708866	down	1.47E-256	**
hsa-miR-26a-1-3p	–1.92492452	down	0.004102228	**
hsa-miR-3611	–1.92492452	down	0.004102228	**
hsa-miR-187-3p	–1.89198508	down	0.000828053	**
hsa-miR-664a-3p	–1.87801528	down	1.82E-41	**
hsa-miR-383-5p	–1.87335512	down	0.03528718	*
hsa-miR-335-3p	–1.84083467	down	7.07E-87	**
hsa-miR-203a-3p	–1.72913403	down	0	**
hsa-miR-3912-3p	–1.71155782	down	2.01E-06	**
hsa-miR-183-3p	–1.69939239	down	0.031012226	*
hsa-miR-135b-5p	–1.69929888	down	3.86E-09	**
hsa-miR-141-5p	–1.69460943	down	6.85E-21	**
hsa-miR-377-5p	–1.65878433	down	7.03E-08	**
hsa-miR-16-5p	–1.65065115	down	0	**
hsa-miR-150-5p	–1.62494834	down	2.07E-49	**
hsa-miR-627-5p	–1.6233869	down	0.000309094	**
hsa-miR-6510-3p	–1.58388025	down	0.000271487	**
hsa-miR-548p	–1.58387326	down	0.026725738	*
hsa-miR-203b-3p	–1.58383438	down	1.74E-09	**
hsa-miR-195-5p	–1.5823761	down	0	**
hsa-miR-141-3p	–1.5772266	down	0	**
hsa-miR-200b-3p	–1.57584304	down	0	**
hsa-miR-944	–1.5589637	down	4.65E-10	**
hsa-miR-200b-5p	–1.53135387	down	2.72E-13	**
hsa-miR-31-5p	–1.5239109	down	6.16E-159	**
hsa-miR-183-5p	–1.52252398	down	2.78E-140	**
hsa-miR-92a-1-5p	–1.52249641	down	0.007046614	**
hsa-miR-493-5p	–1.51904529	down	6.20E-36	**
hsa-miR-320d	1.58604035	up	0.004519782	**
hsa-miR-524-3p	1.69892552	up	4.81E-139	**
hsa-miR-7704	1.8311765	up	0.000268926	**
hsa-miR-450a-1-3p	2.00090764	up	0.021183756	*
hsa-miR-185-5p	2.03429793	up	1.64E-39	**
hsa-miR-503-5p	2.10316253	up	1.37E-29	**
hsa-miR-122-5p	2.13865463	up	0.00090565	**
hsa-miR-1-3p	2.40555691	up	2.02E-13	**
hsa-miR-7-5p	2.40555691	up	2.02E-13	**
hsa-miR-520e	2.41594514	up	0.002562365	**
hsa-miR-1269b	3.39374391	up	3.56E-05	**
hsa-miR-1268a	3.8087166	up	0.000515933	**
hsa-miR-1268b	3.8087166	up	0.000515933	**

Ctr, matched normal skin tissue; Tum, infantile hemangioma skin tissue.