Table 1. Immunohistochemical results of glucose metabolism-related genes in SPN.
Case# | Gender | Age | Tumor Size (cm) | 18FDG-uptake pattern | GLUT1 | HK1 | ENO2 | PKM2 | Ki-67 | Necrosis |
---|---|---|---|---|---|---|---|---|---|---|
1 | Female | 25 | 5.6 | Hot | + | + | + | +/- | < 1% | - |
2 | Female | 46 | 5 | Defective | - | ++ | + | + | < 1% | - |
3 | Female | 38 | 3.5 | Mixed | + | ++ | + | N/A | < 1% | + |
4 | Female | 28 | 5 | Defective | + | N/A | + | N/A | < 1% | + |
5 | Female | 28 | 6.8 | Hot | + | N/A | + | N/A | < 1% | + |
6 | Female | 24 | 8.2 | Hot | + | ++ | + | + | < 1% | - |
7 | Female | 32 | 1.7 | Hot | + | ++ | + | + | 1-2% | - |
8 | Female | 25 | 4.9 | Defective | + | ++ | + | + | 1–2% | - |
9 | Female | 31 | 5.3 | Defective | + | N/A | + | N/A | 0% | + |
10 | Female | 46 | 6.5 | Defective | + | N/A | + | N/A | 0% | + |
11 | Female | 45 | 2.3 | Mixed | + | ++ | + | + | < 1% | - |
12 | Female | 12 | 10.1 | Mixed | + | ++ | + | + | 3% ≤ | - |
13 | Female | 25 | 12.3 | Hot | + | N/A | + | N/A | 1–2% | + |
14 | Female | 35 | 1.3 | Hot | + | ++ | + | + | 1–2% | - |
15 | Female | 24 | 5.7 | Hot | + | ++ | + | + | < 1% | - |
16 | Female | 62 | 1.5 | Hot | + | ++ | + | + | < 1% | - |
17 | Female | 35 | 1.6 | Mixed | + | ++ | + | + | < 1% | - |
18 | Female | 14 | 6.9 | Hot | - | ++ | + | +/- | 3% ≤ | - |
19 | Female | 19 | 3.5 | Mixed | - | ++ | + | + | 1–2% | - |
20 | Female | 47 | 4.2 | Hot | + | ++ | + | + | < 1% | - |
21 | Male | 30 | 3.8 | Hot | + | ++ | + | + | < 1% | - |
22 | Female | 48 | 1.5 | Defective | + | ++ | + | + | < 1% | - |
23 | Female | 41 | 2.5 | Defective | + | N/A | + | N/A | < 1% | + |
24 | Female | 38 | 6.5 | Hot | + | N/A | + | N/A | < 1% | + |
25 | Female | 46 | 2 | Defective | + | ++ | + | + | 1–2% | - |
26 | Female | 28 | 8 | Defective | + | + | + | +/- | 3% ≤ | - |
27 | Female | 16 | 7 | Hot | + | N/A | + | N/A | < 1% | - |
28 | Female | 45 | 3 | - | - | N/A | + | +/- | < 1% | + |
29 | Female | 43 | 5.2 | Defective | - | N/A | + | +/- | < 1% | + |
30 | Female | 22 | 8.5 | Hot | + | + | + | + | 1–2% | - |
31 | Female | 40 | 8.3 | Hot | + | ++ | + | + | 1–2% | - |
32 | Female | 35 | 1.6 | Hot | + | ++ | + | + | < 1% | - |
33 | Female | 38 | 2 | Hot | + | ++ | + | N/A | 1–2% | - |
34 | Female | 40 | 2.7 | Hot | + | + | + | N/A | < 1% | - |
35 | Female | 42 | 1.5 | Hot | + | ++ | + | + | 1–2% | - |
36 | Female | 23 | 5 | Hot | + | ++ | + | +/- | < 1% | - |
N/A; not available due to necrosis, immunohistochemistry score (-; negative, +/-; weak, +; moderate, ++; strong)