Table 4. Correlation between staining intensity of glucose metabolism-related genes and microscopic malignant features of SPNs.
Microscopic malignant features | P-value | |||
---|---|---|---|---|
Absent (N = 29) | Present (N = 7) |
|||
GLUT1 | - | 4 | 1 | 1.000 |
+ | 25 | 6 | ||
HK1* | + | 3 | 1 | 1.000 |
++ | 17 | 5 | ||
PKM2* | +/- | 6 | 0 | 0.280 |
+ | 14 | 6 | ||
Necrosis | - | 20 | 6 | 0.645 |
+ | 9 | 1 | ||
Ki-67 | 0 | 2 | 0 | 0.781 |
< 1 | 15 | 6 | ||
1–2 | 10 | - | ||
3 ≤ | 2 | 1 | ||
Clinical pattern 18FDG-uptake Defective |
Hot+Mixed | 17 | 7 | 0.070 |
12 | 0 |
* 10 cases were not included due to poor staining.