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. 2018 Jan 4;9(15):12079–12100. doi: 10.18632/oncotarget.23951

Figure 3. Venn diagrams showing the overlap of proteins in the thyroid cystic fluid, PTC cell secretome, and PTC tissue microarray datasets.

Figure 3

(A) The number of proteins identified in thyroid cystic fluid samples from PTC patients and patients with benign lesions. (B) The numbers of proteins identified in the secretomes of the PTC cell lines, CGTH W3 and BHP 7-13. (C) The numbers of up-regulated genes in the two PTC tissue transcriptome datasets. (D) Integrated analysis of the PTC cystic fluid proteome (191 proteins), the PTC cell secretome dataset (2105 proteins), and the up-regulated genes in the two PTC tissue transcriptome datasets (4681 genes). This analysis identified seven proteins as strong PTC biomarker candidates.