Table 3. The expression profile of EPS-miRNAs in health group and disease group.
Stably abundant EPS-miRNAs | |||||||
---|---|---|---|---|---|---|---|
Health Group | Disease Group | ||||||
MiRNA | H1 | H2 | H2/H1 Fold | MiRNA | P1 | P2 | P2/P1 Fold |
let-7d-5p | 662.26 | 363.77 | 0.55 | let-7a-5p | 77578.94 | 74867.08 | 0.97 |
let-7i-5p | 194.90 | 142.90 | 0.73 | let-7b-5p | 70649.18 | 72327.38 | 1.02 |
miR-101-3p | 565.28 | 812.94 | 1.44 | let-7c-5p | 32056.15 | 30586.95 | 0.95 |
miR-103a-3p | 7008.23 | 5257.84 | 0.75 | let-7d-5p | 986.45 | 911.52 | 0.92 |
miR-106a-5p | 451.21 | 715.18 | 1.59 | let-7e-5p | 1931.48 | 1411.38 | 0.73 |
miR-106b-5p | 267.01 | 170.85 | 0.64 | let-7f-5p | 46791.44 | 37261.10 | 0.80 |
miR-107 | 4445.80 | 2609.13 | 0.59 | let-7g-5p | 2949.97 | 3431.39 | 1.16 |
miR-10b-5p | 227.06 | 234.15 | 1.03 | let-7i-5p | 248.84 | 151.46 | 0.61 |
miR-146b-5p | 148.62 | 183.89 | 1.24 | miR-103a-3p | 8726.56 | 6389.46 | 0.73 |
miR-148a-3p | 1039.77 | 1387.57 | 1.33 | miR-107 | 3901.75 | 3193.78 | 0.82 |
miR-16-5p | 465.34 | 274.54 | 0.59 | miR-128-3p | 132.89 | 101.10 | 0.76 |
miR-17-5p | 155.85 | 211.16 | 1.35 | miR-141-3p | 143.37 | 93.19 | 0.65 |
miR-185-5p | 271.23 | 470.46 | 1.73 | miR-146b-5p | 401.32 | 327.34 | 0.82 |
miR-191-5p | 2368.42 | 2393.83 | 1.01 | miR-151a-5p | 154.21 | 110.94 | 0.72 |
miR-19b-3p | 185.37 | 286.77 | 1.55 | miR-152-3p | 191.48 | 111.11 | 0.58 |
miR-200b-5p | 136.13 | 266.78 | 1.96 | miR-16-5p | 377.46 | 306.53 | 0.81 |
miR-200c-3p | 838.58 | 469.00 | 0.56 | miR-185-5p | 605.11 | 860.33 | 1.42 |
miR-21-5p | 7895.49 | 5713.39 | 0.72 | miR-191-5p | 3585.84 | 4295.99 | 1.20 |
miR-23a-3p | 524.39 | 452.66 | 0.86 | miR-192-5p | 350.97 | 252.88 | 0.72 |
miR-23b-3p | 294.70 | 171.79 | 0.58 | miR-193a-5p | 277.84 | 191.10 | 0.69 |
miR-24-3p | 412.39 | 619.53 | 1.50 | miR-193b-3p | 244.93 | 130.17 | 0.53 |
miR-25-3p | 565.79 | 966.97 | 1.71 | miR-200b-3p | 234.24 | 150.10 | 0.64 |
miR-26a-5p | 1139.43 | 704.41 | 0.62 | miR-200c-3p | 929.41 | 904.72 | 0.97 |
miR-29a-3p | 5751.36 | 2919.51 | 0.51 | miR-203a | 103.77 | 150.60 | 1.45 |
miR-29b-3p | 406.52 | 303.19 | 0.75 | miR-21-5p | 11336.04 | 6586.28 | 0.58 |
miR-29c-3p | 5565.32 | 4447.91 | 0.80 | miR-23a-3p | 1029.99 | 913.55 | 0.89 |
miR-30a-5p | 672.17 | 591.82 | 0.88 | miR-23b-3p | 401.98 | 231.74 | 0.58 |
miR-30b-5p | 906.03 | 551.36 | 0.61 | miR-24-3p | 197.48 | 359.90 | 1.82 |
miR-30c-5p | 356.20 | 328.70 | 0.92 | miR-26a-5p | 2804.81 | 1775.80 | 0.63 |
miR-30d-5p | 823.51 | 846.46 | 1.03 | miR-26b-5p | 3901.57 | 2998.89 | 0.77 |
miR-30e-5p | 132.89 | 104.22 | 0.78 | miR-27a-3p | 136.71 | 118.82 | 0.87 |
miR-331-3p | 112.99 | 110.03 | 0.97 | miR-29a-3p | 3944.10 | 2087.09 | 0.53 |
miR-363-3p | 885.33 | 1162.40 | 1.31 | miR-30a-5p | 699.35 | 419.27 | 0.60 |
miR-365a-3p | 231.99 | 377.05 | 1.63 | miR-30b-5p | 739.22 | 396.40 | 0.54 |
miR-365b-3p | 231.99 | 377.05 | 1.63 | miR-30c-5p | 391.62 | 262.67 | 0.67 |
miR-423-5p | 2760.53 | 3811.92 | 1.38 | miR-30d-5p | 1312.97 | 800.01 | 0.61 |
miR-574-3p | 297.33 | 331.06 | 1.11 | miR-320a | 5499.88 | 3203.94 | 0.58 |
miR-598-3p | 264.28 | 210.18 | 0.80 | miR-342-3p | 309.05 | 216.90 | 0.70 |
miR-92a-3p | 391.45 | 625.79 | 1.60 | miR-375 | 46550.06 | 23526.90 | 0.51 |
miR-99a-5p | 907.30 | 492.77 | 0.54 | miR-423-5p | 4458.66 | 3858.82 | 0.87 |
miR-99b-5p | 295.22 | 298.59 | 1.01 | miR-574-3p | 196.41 | 134.56 | 0.69 |
miR-744-5p | 168.31 | 126.65 | 0.75 | ||||
miR-92a-3p | 1527.38 | 818.61 | 0.54 | ||||
miR-93-5p | 359.04 | 264.68 | 0.74 | ||||
miR-99a-5p | 584.47 | 441.94 | 0.76 | ||||
miR-99b-5p | 368.74 | 325.30 | 0.88 |
The top 10 EPS-miRNAs | ||||
---|---|---|---|---|
Rank | Health Group | Disease Group | ||
H1 subgroup | H2 subgroup | P1 subgroup | P2 subgroup | |
1 | let-7a-5p | miR-375 | let-7a-5p | let-7a-5p |
137505 | 36790 | 77578 | 74867 | |
2 | let-7f-5p | let-7b-5p | let-7b-5p | let-7b-5p |
87358 | 31665 | 70649 | 72327 | |
3 | let-7b-5p | let-7a-5p | let-7f-5p | let-7f-5p |
84877 | 24345 | 46791 | 37261 | |
4 | let-7c-5p | let-7f-5p | miR-375 | let-7c-5p |
51008 | 15340 | 46550 | 30586 | |
5 | let-7g-5p | miR-193a-3p | let-7c-5p | miR-375 |
9448 | 11574 | 32056 | 23526 | |
6 | miR-375 | let-7c-5p | miR-21-5p | miR-21-5p |
8782 | 9505 | 11336 | 6586 | |
7 | miR-26b-5p | miR-21-5p | miR-103a-3p | miR-103a-3p |
8126 | 5713 | 8726 | 6389 | |
8 | miR-21-5p | miR-103a-3p | miR-193a-3p | miR-140-3p |
7895 | 5257 | 5976 | 4804 | |
9 | miR-103a-3p | miR-29c-3p | miR-29c-3p | miR-191-5p |
7008 | 4447 | 5866 | 4295 | |
10 | miR-29a-3p | miR-423-5p | miR-320a | miR-423-5p |
5751 | 3811 | 5499 | 3858 |