Table 2. HRs and 95% CIs for patient survival or disease progression in association with TRIM29 expression in enrolled studies.
| First author, publication year | Main assay method | Case number | OS | DFS/RFS | PFS/MFS | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| High expression | low expression | Total | HR (95% CI) | P Value | HR (95% CI) | P Value | HR (95% CI) | P Value | ||
| Xu, 2017 | qRT-PCR | 41 | 15 | 56 | 1.400 (0.680–2.860) | 0.026 | 1.300 (0.540–3.150) | 0.030 | NM | NM |
| Xu, 2016 | IHC | 62 | 88 | 150 | 3.076 (1.544–6.129) | 0.001 | 2.830 (1.495–5.356) | 0.001 | NM | NM |
| Song, 2015 | IHC | 79 | 241 | 320 | 2.102 (1.069–3.193) | 0.003 | 1.384 (0.982–1.952) | 0.064 | NM | NM |
| Harris, 2015 | qRT-PCR | NM | NM | 43 | 0.210 (1.069–3.193) | 0.006 | NM | NM | 0.024 (0.003–0.909) |
0.000 |
| Harris, 2015 | IHC | NM | NM | 43 | 0.260 (0.120–0.580) | 0.000 | NM | NM | 0.154 (0.027–0.909) |
0.000 |
| Sun, 2014 | IHC | 109 | 77 | 186 | 2.180 (1.324–4.198) | 0.011 | 1.630 (1.180–2.260) | 0.008 | NM | NM |
| Jiang, 2013 | IHC | 65 | 86 | 151 | 0.431 (0.220-0.841) | 0.014 | 2.370 (1.203–4.651) | < 0.001 | NM | NM |
| Fristrup, 2013 | IHC | NM | NM | 283 | 0.810 (0.500–1.290) | 0.366 | NM | NM | 0.600 (0.390–0.930) |
0.023 |
| Fristrup, 2013 | IHC | NM | NM | 576 | 0.795 (0.505–1.251) | 0.321 | NM | NM | 0.790 (0.510–1.250) |
0.321 |
| Lai, 2013 | IHC | 25 | 34 | 59 | 2.558 (1.435–4.566) | < 0.01 | NM | NM | NM | NM |
| Zhou, 2011 | IHC | NM | NM | 56 | 5.300 (1.32–20.774) | 0.017 | NM | NM | NM | NM |
| Zhao, 2012 | IHC | NM | NM | 42 | 1.950 (1.260–3.030) | 0.044 | NM | NM | NM | NM |
| Kosaka, 2007 | qRT-PCR | 62 | 62 | 124 | 1.050 (0.780–1.440) | 0.730 | NM | NM | NM | NM |
OS, overall survival; DFS, disease-free survival; MFS, metastasis-free survival; RFS, recurrence-free survival; PFS, progression-free survival; DSS, disease-specific survival; NSCLC, non-small cell lung cancer; OCSCC, oral cavity squamous cell carcinoma; SCC, squamous cell carcinoma; HR, hazard ratio; IHC, Immunohistochemistry; qRT-PCR, quantitative reverse transcription polymerase chain reaction; NM: not mentioned; CI, confidence interval; TRIM29, tripartite motif-containing protein 29.