(A) Forest plot (A1, RE) and funnel plot (A2, RE) showing 6 of 15 studies with CICCs, stratified by patients populations and pharmacological deep vein thrombosis prophylaxis. Forest plot showing odds ratio (OR) of development of thrombosis in patients with central inserted central catheters (CICCs), stratified by patients populations and pharmacological deep vein thrombosis prophylaxis. (B) Forest plot (B1,RE; B3,FE) and funnel plot (B2,RE; B4,FE) showing 8 studies of 2639 patients with CICCs, stratified by pharmacological deep vein thrombosis prophylaxis. Forest plot showing odds ratio (OR) of development of mortality rate in patients with central inserted central catheters (CICCs). (C) Forest plot (C1, C2) showing 3 studies with CICCs, stratified by the same pharmacological deep vein thrombosis prophylaxis -- warfarin. PICC = peripherally inserted central catheter; CICC = central inserted central catheter; FE = fixed effect; RE = random effect; OR = odds ratio; RR = risk ratio; VTE = venous thromboembolism.