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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: J Autoimmun. 2017 Oct 23;88:75–82. doi: 10.1016/j.jaut.2017.10.004

Figure 2. Association between L1 retroelements and members of the methylation machinery.

Figure 2

Relative expression of L1 retroelements and DNMT3B, MeCP2, DNMT1 and LSH was measured by real-time PCR in MSG biopsy specimens obtained from SS-low risk and SS-lymphoma patients. Association between L1 mRNA levels and members of the methylation machinery were tested using Spearman’s nonparametric correlation test. L1 expression was positively correlated with DNMT3B, MeCP2, DNMT1 transcripts (r=0.62, p<0.0001, r= 0.60, p=0.0001, r=0.69, p<0.0001 respectively, panels A–C) and negatively correlated with LSH mRNA levels (r=−0.42, p=0.03, panel D).