Skip to main content
. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Physiol Behav. 2017 Dec 5;187:67–78. doi: 10.1016/j.physbeh.2017.11.022

FIGURE 4.

FIGURE 4

A) Graphic showing reservoirs of metabolic substrates in brain and provision routes based on the lactate-shuttle hypothesis. GlUT = glucose transporter; MCT = monocarboxylate transporter; 3βHB = 3-β hydroxybutyrate; TCA = tricarboxylic acid cycle; G-6-P = glucose-6-phosphate. Adapted from [144]. B) Schematic of data collected in ovariectomized females with and without 4.5 ug/kg estradiol benzoate and age-matched males. Bars depict relative brain concentrations of glucose and lactate measured from extracellular fluid dialysate and the ketone 3βHB from whole tissue homogenates.