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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Nanomedicine. 2017 Oct 24;14(2):397–404. doi: 10.1016/j.nano.2017.10.004

Figure 1. Contrast Agent delivery to the inner ear.

Figure 1

There are two routes available for the delivery of contrast agents. (Figure A) Systemic delivery is inefficient with the distribution problems being exacerbated by the blood labyrinth barrier. This can impede contrast agent delivery and may result in insufficient amounts of the agent reaching the inner ear. Transtympanic, (Figure B) local delivery efficiently delivers the contrast agent into the cochlea.