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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Exp Hematol. 2017 Dec 27;59:40–50.e3. doi: 10.1016/j.exphem.2017.12.009

Figure 2. DEK expression is required for proper response to repeated radiation exposure.

Figure 2

(A) Diagram of experimental methods, in which 6 mice from each genotype received four sublethal 7Gy doses of radiation over the course of 110 days. (B) Survival curves comparing DEK KO versus WT mice following multiple doses of radiation (p<0.01). (C) Bone marrow from DEK WT and KO mice was collected and transplanted into lethally irradiated CD45.2 CD57Bl/6 mice at four doses: 10×103, 30×103, 100×103, and 300×103 cells (n=8 mice/group, total of 8 groups).