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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Exp Hematol. 2017 Dec 27;59:40–50.e3. doi: 10.1016/j.exphem.2017.12.009

Figure 3. DEK loss induces radioresistance in transient repopulating progenitor cells.

Figure 3

(A) Diagram of experimental methods in which bone marrow cells were collected from irradiated WT (n=5) or KO (n=4) donor mice and co-transplanted with competitor bone marrow cells from BoyJ mice prior to implantation into lethally radiated BoyJ mice. (B) Analysis of peripheral blood chimerism over 28 days, showing percentage of total CD45.2 nucleated cells from WT vs. KO donor mice, as well as B220+ B cells (C), CD3+ T cells (F), and both Gr1+ and Mac1+ myeloid cells (D, E, G, H). Irradiated Dek KO cells show better recovery and less stress after transplantation.