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. 2018 Mar 9;8:4239. doi: 10.1038/s41598-018-19993-9

Table 2.

Mean Number of Days (Min, Max) between Baseline (T0) and Follow-Ups (T1, T2, and T3).

CTR ERGO MAZE COMBO p
T0,T1 21.35 (20, 24) 20.41 (16, 22) 20.91 (17, 24) 20.83 (17, 23) 0.029
T0,T2 55.88 (46, 61) 59.59 (53, 79) 55.74 (52, 60) 55.83 (51, 64) 0.007
T0,T3 106.57 (104, 133) 105.80 (95, 113) 105.23 (100, 118) 104.91 (100, 111) 0.553

Values refer to the time points of cognitive assessment, respectively. We obtained p-values by applying analysis of variance (ANOVA). To account for between-subjects differences in the number of days since baseline T0, we applied linear mixed modeling to analyze longitudinal changes. COMBO = group undergoing cycling exercise and maze training, CTR = passive controls, ERGO = group undergoing cycling exercise, MAZE = group undergoing maze training.