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. 2018 Mar 9;8:4232. doi: 10.1038/s41598-018-22708-9

Table 2.

Contribution of each pattern to the G2 and Pearson chi-squared test statistics. “+” = positive, “−” = negative, “?” = indeterminate. LFA = lateral flow assay; ELISA = enzyme-linked immunosorbent assay; MBA = multiplex bead array. Model with two latent classes utilizes Model 19 from Table 1 and Model with three latent classes utilizes Model 22 from Table 1.

Model with two latent classes Model with three latent classes
MBA ELISA LFA (blood) LFA (serum) N Estimated probability positive Estimated probability negative Expected N Contribution to χ2 Contribution to G2 Estimated probability positive Estimated probability negative Estimated probability indeterminate Expected N Contribution to χ2 Contribution to G2
164 0.00 1.00 162.63 0.01 2.75 0.00 1.00 0.00 164.10 0.00 −0.21
? 3 0.00 1.00 3.01 0.00 −0.01 0.00 0.96 0.04 2.90 0.00 0.20
 +  4 0.01 0.99 3.86 0.01 0.29 0.00 0.88 0.12 3.86 0.01 0.29
+ + 1 0.37 0.63 1.06 0.00 −0.11 0.00 0.00 1.00 1.04 0.00 −0.07
? 4 0.00 1.00 5.28 0.31 −2.21 0.00 0.97 0.03 3.97 0.00 0.06
? ? + 1 1.00 0.00 0.06 15.01 5.66 0.01 0.00 0.99 0.32 1.43 2.27
? + 1 0.39 0.61 0.03 31.36 7.01 0.00 0.00 1.00 0.14 5.44 3.98
? + + 1 0.97 0.03 0.78 0.06 0.50 0.10 0.00 0.90 1.35 0.09 −0.60
+ + + 1 1.00 0.00 1.81 0.37 −1.19 1.00 0.00 0.00 0.86 0.02 0.31
? 3 0.00 1.00 3.83 0.18 −1.46 0.00 0.93 0.07 3.05 0.00 −0.10
? + + 3 0.98 0.02 0.93 4.61 7.03 0.00 0.00 1.00 2.19 0.30 1.88
? ? 1 0.00 1.00 0.12 6.19 4.17 0.00 0.22 0.78 0.31 1.55 2.36
? ? ? 1 0.94 0.06 0.04 24.35 6.54 0.00 0.00 1.00 0.30 1.60 2.39
? ? + 3 0.99 0.01 0.26 29.01 14.70 0.00 0.00 1.00 1.16 2.91 5.69
? ? + + 2 1.00 0.00 1.77 0.03 0.49 0.00 0.00 1.00 2.58 0.13 −1.02
+ 2 0.00 1.00 2.08 0.00 −0.15 0.00 0.77 0.23 1.99 0.00 0.02
+ ? 1 0.85 0.15 0.25 2.27 2.78 0.00 0.04 0.96 0.60 0.26 1.01
+ + 3 0.97 0.03 1.57 1.30 3.89 0.01 0.01 0.98 2.26 0.24 1.69
+ ? ? 1 1.00 0.00 0.12 6.59 4.27 0.00 0.00 1.00 0.28 1.88 2.56
+ ? + 2 1.00 0.00 0.82 1.68 3.55 0.01 0.00 0.99 1.29 0.39 1.74
+ + + 5 1.00 0.00 10.52 2.89 −7.43 0.04 0.00 0.96 5.14 0.00 −0.28
+ ? + 2 1.00 0.00 2.94 0.30 −1.55 0.22 0.00 0.78 3.33 0.53 −2.04
+ ? ? + 2 1.00 0.00 1.59 0.10 0.91 0.17 0.00 0.83 1.83 0.02 0.36
+ ? + 1 1.00 0.00 0.32 1.48 2.30 0.00 0.00 1.00 0.65 0.18 0.85
+ ? + + 16 1.00 0.00 20.31 0.92 −7.64 0.62 0.00 0.38 15.32 0.03 1.40
+ + + 5 1.00 0.00 7.04 0.59 −3.42 1.00 0.00 0.00 4.64 0.03 0.74
+ + ? + 2 1.00 0.00 3.81 0.86 −2.58 1.00 0.00 0.00 2.01 0.00 −0.03
+ + + ? 1 1.00 0.00 0.54 0.38 1.22 1.00 0.00 0.00 0.85 0.03 0.32
+ + + + 61 1.00 0.00 48.59 3.17 27.75 1.00 0.00 0.00 61.53 0.00 −1.05