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. 2018 Mar 5;5:47. doi: 10.3389/fmed.2018.00047

Table 3.

Overall best signed and unsigned correlation results between Raman vs. CuBiAn, and Raman vs. LC-MS measurements.

Off-line measurements Highest absolute correlation R Highest positive correlation R
Raman vs. CuBiAn (days 1–10) Glucose 0.9576 N/A
Lactate −0.9543 0.9502
Glutamine 0.8465 N/A
Glutamate −0.8621 0.836
Ammonia 0.9352 N/A
Cell concentration* −0.9308 0.905
Viability* −0.6543 0.6111

Raman vs. LC-MS (days 1–9) Glucose N/A 0.9713
Lactate N/A 0.9517
Glutamine N/A 0.8386
Glutamate −0.8449 0.8445
Ammonia N/A N/A
Cell concentration* −0.9374 0.9213
Viability* −0.5977 0.2466

*Cell concentration and viability measured by ViCell.