Table 1.
Comparison of ingredient properties among Dangguiliuhuang decoction (DGLHD).
| Primary ingredients | Ministerial ingredients | Adjunctive ingredient | |||||
|---|---|---|---|---|---|---|---|
| Index | AG | RR | RRP | GC | CC | SB | AM |
| MW | 203.18 ± 115.77ΔΔ | 439.96 ± 209.05∗∗ | 361.52 ± 174.31∗∗, # | 286.99 ± 141.05ΔΔ | 342.19 ± 132.38∗, Δ | 277.74 ± 106.74##, ΔΔ | 418.03 ± 238.65 |
| MLogP | 3.26 ± 2.16ΔΔ | -1.10 ± 3.20∗∗, ΔΔ | 0.06 ± 4.05∗∗, ΔΔ | 3.10 ± 2.21ΔΔ | 2.55 ± 1.87Δ | 4.10 ± 3.35∗∗, ##, ΔΔ | 1.47 ± 2.62 |
| HDon | 0.76 ± 1.12ΔΔ | 6.18 ± 3.52∗∗, ΔΔ | 4.60 ± 3.48∗∗, # | 1.34 ± 1.75ΔΔ | 1.77 ± 1.72ΔΔ | 1.44 ± 1.93ΔΔ | 4.16 ± 2.92 |
| HAcc | 2.00 ± 2.47Δ | 10.47 ± 6.04∗∗, ΔΔ | 7.88 ± 5.46∗∗, # | 3.74 ± 2.75ΔΔ | 5.50 ± 2.21∗∗, ΔΔ | 3.48 ± 3.23##, ΔΔ | 7.72 ± 4.81 |
| OB | 36.01 ± 19.39 | 24.87 ± 22.27∗∗ | 27.28 ± 25.45∗∗ | 34.51 ± 17.00 | 36.09 ± 23.55 | 31.42 ± 18.74 | 32.32 ± 23.70 |
| DL | 0.09 ± 0.16ΔΔ | 0.41 ± 0.25∗∗ | 0.32 ± 0.27∗∗ | 0.33 ± 0.32 | 0.42 ± 0.31 | 0.23 ± 0.22∗∗, ##, Δ | 0.31 ± 0.29 |
AG, angelica; RR, radix rehmanniae; RRP, radix rehmanniae praeparata; SB, scutellaria baicalensis; CC, coptis chinensis; GC, golden cypress; AM, astragalus membranaceus.∗P < 0.05, ∗∗P < 0.01 compared to AG or GC; #P < 0.05, ##P < 0.01 compared to RR or CC; ΔP < 0.05, ΔΔP < 0.01 compared to AM.