Table 1.
Clinical characteristics of stroke patients and controls.
| Variables | Controls (n = 95) | Stroke Patients (n = 95) | p-Value* |
|---|---|---|---|
| Gender, male n (%) | 47 (39.4) | 57 (58.6) | 0.155 |
| Age (mean ± SD) | 69.65 ± 8.12 | 67.35 ± 10.13 | 0.085 |
| BMI (mean ± SD) | 27.16 ± 3.58 | 27.44 ± 3.25 | 0.582 |
| Hypertension n (%) | 42 (44.2) | 70 (75.3) | <0.001 |
| Diabetes n (%) | 11 (11.6) | 23 (24.7) | 0.012 |
| Smoking n (%) | 31 (32.6) | 47 (50.5) | 0.006 |
| Alcohol n (%) | 21 (22.1) | 19 (20.4) | 0.922 |
| Antiplatelet/anticoagulant n (%) | 25 (26.3) | 36 (38.7) | 0.038 |
| National Institutes of Health Stroke Scale Score (mean ± SD) | 8.95 ± 5.64 | ||
| Total cholesterol (mean ± SD) | 205.9 ± 39.58 | 197.7 ± 47.69 | 0.204 |
| HDL cholesterol (mean ± SD) | 50.1 ± 15.99 | 48.3 ± 16.75 | 0.472 |
| LDL cholesterol (mean ± SD) | 115.6 ± 31.34 | 110.2 ± 36.17 | 0.287 |
| Triglyceride (mean ± SD) | 144.4 ± 61.46 | 161.4 ± 90.30 | 0.138 |
| Serum TNF-related apoptosis-inducing ligand (TRAIL) level (pg/ml) (mean ± SD) | 156.7 ± 50.50 | 83.99 ± 23.43 | <0.0001 |
| TRAIL mRNA fold (mean ± SD) | 1.638 ± 1.628 | 9.36 ± 10.64 | <0.0001 |
*The p-value was calculated by comparing controls and stroke patients.
The significant comparisons are displayed in bold.