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. 2018 Mar 9;8:4236. doi: 10.1038/s41598-018-22495-3

Table 2.

Factors associated with positive of the T-SPOT.TB diagnostic tests in smear-negative PTB patients.

Factors Total N = 858 No.(%)
with positive results
Univariate OR (95% CI) Multivariate adjusted OR (95% CI) P
Gender
 Male 584 508(87.0) Reference
 Female 274 234(85.4) 0.875(0.579–1.323)
Age
 <45years 469 425(90.6) 2.555(1.607–4.061) 2.132(1.302–3.489) 0.003
 45–59years 193 162(83.9) 1.382(0.825–2.315) 1.287(0.763–2.171) 0.345
 ≥60years 196 155(79.1) Reference Reference
Smoking
 No 612 526(85.9) Reference
 Yes 246 216(87.8) 1.177(0.755–1.837)
Diabetes
 No 794 687(86.5) Reference
 Yes 64 55(85.9) 0.952(0.457–1.982)
BMI
 <18.5 174 158(90.8) Reference
 ≥18.5 684 584(85.4) 0.591(0.339–1.031)
Contact of TB
 No 907 694(86.0) Reference
 Yes 51 48(94.1) 2.605(0.798–8.506)
BCG
 No 442 371(83.9) Reference
 Yes 416 351(84.3) 1.078(0.757–1.354)
TB Category
 New 715 626(87.6) Reference Reference 0.211
 Retreatment 143 116(81.1) 0.611(0.380–0.981) 0.730(0.446–1.195)
Course
 <1 month 236 210(89.0) Reference
 ≥1month 622 532(85.5) 0.732(0.460–1.165)
Albumin
 Decreased 145 114(78.6) Reference Reference 0.046
 Normal 713 628(88.1) 2.009(1.272–3.173) 1.629(1.008–2.631)