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. 2018 Mar 9;9(3):387. doi: 10.1038/s41419-018-0399-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a IVIS images of BALB/c nu/nu mice injected with MHCC-LM3-shELF3 cells and MHCC-LM3-shcontrol cells. b The total photon flux were measured and analyzed using the Living Image software, and the results showed less total metastatic foci in the MHCC-LM3-shELF3 group. c Representative images of hematoxylin and eosin staining of xenograft tumors (magnification ×100, scale bar:200μm). The region in the black square was further enlarged (magnificantion ×400, scale bar:50μm). d Representative IHC images of ELF3 and E-cadherin in xenograft tumors (magnification ×100, scale bar:200μm). The region in the black square was further enlarged (magnification ×400, scale bar:50μm). p < 0.05 was considered statistically significant. *p < 0.05, **p < 0.01, and ***p < 0.001 based on the Student t test