Table 2.
Frequencies of chromosomal abnormalities detected in POCs of groups of patients with different modes of conception and different age groups
| Abnormality type | Frequency of different abnormality types in groups of patients with different conception modes | P (χ2) | ||||
| General group, % | ICSI group, % | Spontaneous conception group, % | ||||
| Trisomy | 59.7 | 68.1 | 54.5 | 0.219 | ||
| Polyploidy | 28.0 | 14.7 | 26.5 | 0.066 | ||
| Monosomy | 7.6 | 8.9 | 6.8 | 0.596 | ||
| Structural abnormality | 7.0 | 5.2 | 8.1 | 0.426 | ||
| Double aneuploidy | 3.8 | 3.1 | 4.2 | 0.683 | ||
| Abnormality rate, % | 50.1 | 51.8 | 49.1 | 0.788 | ||
| Frequency of chromosomal abnormalities in POCs of different age groups | ||||||
| Age | N | Karyotype | P (Fisher’s exact test) | |||
| Normal, N | Normal, % | Abnormal, N | Abnormal, % | |||
| < 25 | 56 | 30 | 53.6 | 26 | 46.4 | – |
| 25–29 | 238 | 129 | 54.2 | 109 | 45.8 | 0.51 |
| 30–34 | 315 | 174 | 55.2 | 141 | 44.8 | 0.47 |
| 35–39 | 258 | 117 | 45.3 | 141 | 54.7 | 0.16 |
| > 40 | 133 | 49 | 36.8 | 84 | 63.2 | P < 0.05* |