Table 3.

Performance of QSAR based predictive models developed on each of the HIV protein inhibitor (IC₅₀) datasets during tenfold training/testing and on independent validation

Serial number	HIV protein	Inhibitor compounds			Number of selected descriptors	Pearson’s correlation coefficient (PCC)		p value
		Total	Training/testing	Independent validation		Training/testing (10×)	Independent validation
1	Protease	1895	1706	189	45	0.78	0.73	1.00e−9
2	Reverse transcriptase	2126	1914	212	61	0.76	0.72	1.00e−7
3	Integrase	1240	1116	124	55	0.74	0.70	1.00e−6