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. 2018 Feb 23;7(1):e4. doi: 10.2196/ijmr.9325

Table 3.

Treatment characteristics of 277 treated tenosynovial giant cell tumor (TGCT) patients.

Treatment Localized-TGCTa (n=67) Diffuse TGCT (n=210)
Initial surgery, n (%)


Arthroscopic synovectomy 38 (57) 113 (53.8)

Open synovectomy (one- or two-staged) 26 (39) 90 (42.9)

Combined arthroscopic/open synovectomy 3 (4) 0 (0.0)

Total joint replacement/(tumor) prosthesis 0 (0) 5 (2.4)

Amputation 0 (0) 2 (1.0)
Adjuvant therapy, n (%) 5 (7) 53 (25.2)

Radiotherapy 4 (6) 18 (8.6)

90-Yttrium 1 (1) 14 (6.7)

Systemic 0 (0) 15 (7.1)

Otherb 0 (0) 6 (2.9)
Recurrent disease, n (%) 24 (36) 146 (69.5)
Additional surgery, n (%) 23 (34) 125 (59.5)

Arthroscopic synovectomy 7 (10) 32 (15.2)

Open synovectomy (one- or two-staged) 10 (15) 74 (35.2)

Combined arthroscopic/open synovectomy 1 (1) 4 (1.9)

Total joint replacement/(tumor) prosthesis 2 (3) 12 (5.7)

Amputation 3 (4) 3 (1.4)

aTGCT: tenosynovial giant cell tumor.

bOther adjuvant therapies were cryosurgery, burning tools, steroid injections, or combination of multiple adjuvant therapies.