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. 2018 Mar 5;9:40. doi: 10.3389/fendo.2018.00040

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Copyright © 2018 García-Delgado, Velasco, Sánchez-Soto, Díaz-García and Hiriart.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Variability of high-voltage-activated (HVA) calcium currents in P20 beta cells. (A) Representative recordings of global calcium currents observed in P20 beta cells with HVA currents higher or less than HVA currents of adult beta cells with or without T-type current. Protocol: voltage ramp from −80 to +60 mV, 500 ms duration, and 0.5 mV/ms slope. (B) Quantification of the P20 beta cells percentage with HVA currents higher (n = 35) and less (n = 43) than HVA currents of adult beta cells. (C) Quantification of the P20 beta cells percentage represented in (B) with and without T-type calcium current.