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. 2018 Mar 9;18:270. doi: 10.1186/s12885-018-4179-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Immunohistochemical expression of CD63 in diffuse astrocytomas. a Gemistocytic tumors showed distinct CD63 expression (arrows), b whereas a more diffuse CD63 staining was seen in tumors with a fibrillary pattern. b, c A faint CD63 expression was detected close to the lumen of the some tumor blood vessels (arrows). d In some of the fibrillary tumors, an increased diffuse perivascular staining was observed (arrows). Scale bar: 30 μm (a, c), 100 μm (b), and 50 μm (d)