Table 1.
Patient characteristics
| Diffuse astrocytoma | Anaplastic astrocytoma | Glioblastoma | |
|---|---|---|---|
| Patients (n) | 23 | 14 | 74 |
| Age | |||
| Mean | 45.0 | 52.2 | 61.4 |
| Range | 2.6–78.5 | 29.9–77.3 | 21.2–78.4 |
| Sex (n) | |||
| Male | 15 | 8 | 48 |
| Female | 8 | 6 | 26 |
| Status (n) | |||
| Alive | 4 | 0 | 1 |
| Dead | 19 | 14 | 73 |
| Over survival (months) | |||
| Median | 57.1 | 18.4 | 8.4 |
| Range | 3.4–267.0 | 2.1–48.3 | 0.08–163.5 |
| IDH statusa | |||
| Mutated | 14 | 4 | 2 |
| Wildtype | 9 | 10 | 72 |
aIDH status was only investigated by immunohistochemistry for glioblastoma patients. For patients diagnosed with diffuse and anaplastic astrocytoma, IDH status was investigated by immunohistochemistry and next generation sequencing (See Materials and Methods section: Immunohistochemistry)
Abbreviations: IDH isocitrate dehydrogenase