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. 2018 Mar 9;18:121. doi: 10.1186/s12879-018-3020-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Minimum spanning tree of the MLSTs of the 62 C. diphtheriae isolates. Each circle corresponds to an ST. The area of each circle corresponds to the number of isolates. Each ST is colour coded according to its corresponding time period of isolation: red – 1950s-1960s, yellow – 1990s-2001, green – 2004-2016. The relationships between the isolates are indicated by the connections between the isolates and the lengths of the branches linking them. The numbers between the circles indicate the number of allelic differences