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. 2018 Mar 9;14:80. doi: 10.1186/s12917-018-1400-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Spongiform change and patterns of PrP^Sc immunoreactivity observed in elk inoculated with the CWD agent. a Intraneuronal immunoreactivity in the hypoglossal nucleus in elk #5 (LL132) elk. b Glial associated immunoreactivity in the cerebellar white matter of elk #5 (LL132). c Glial associated immunoreactivity in the lateral geniculate nucleus of elk #5 (LL132). a-c immunostained using monoclonal anti-PrP antibody F99/96.7.1, original magnification 40×