Table 2.
Diagnosis category* | Patients with primary Sjögren’s syndrome (n=160; person-years=1592) |
Comparators (n=466; person-years=4660) |
Rate ratio (95% CIl) | ||
Number of hospitalisations | Rate per 100 person-years | Number of hospitalisations | Rate per 100 person-years | ||
Overall | 385 | 24.2 | 899 | 19.3 | 1.25 (1.11 to 1.41) |
Infectious and parasitic diseases | 12 | 0.8 | 30 | 0.6 | 1.20 (0.59 to 2.24) |
Neoplasms | 18 | 1.1 | 45 | 1.0 | 1.19 (0.67 to 1.99) |
Endocrine, nutritional and metabolic diseases and immunity disorders | 24 | 1.5 | 39 | 0.8 | 1.82 (1.08 to 2.98) |
Mental illness | 13 | 0.8 | 31 | 0.7 | 1.25 (0.63 to 2.30) |
Diseases of the nervous system and sense organs | 14 | 0.9 | 33 | 0.7 | 1.27 (0.65 to 2.28) |
Diseases of the circulatory system | 74 | 4.7 | 186 | 4.0 | 1.17 (0.89 to 1.52) |
Diseases of the respiratory system | 39 | 2.5 | 89 | 1.9 | 1.29 (0.87 to 1.86) |
Diseases of the digestive system | 28 | 1.8 | 94 | 2.0 | 0.88 (0.57 to 1.31) |
Diseases of the genitourinary system | 22 | 1.4 | 61 | 1.3 | 1.07 (0.64 to 1.70) |
Complications of pregnancy; childbirth and the puerperium | 9 | 0.6 | 20 | 0.4 | 1.36 (0.58 to 2.82) |
Diseases of the skin and subcutaneous tissue | 7 | 0.4 | 17 | 0.4 | 1.25 (0.48 to 2.80) |
Connective tissue† | 52 | 3.3 | 103 | 2.2 | 1.49 (1.05 to 2.05) |
Injury and poisoning | 45 | 2.8 | 91 | 2.0 | 1.46 (1.01 to 2.06) |
Symptoms, signs and ill-defined conditions | 20 | 1.3 | 42 | 0.9 | 1.41 (0.81 to 2.35) |
*The following four categories with <5 hospitalisation in patients with primary Sjögren syndrome were excluded: diseases of the blood and blood-forming organs, congenital anomalies, certain conditions originating in the perinatal period, residual codes and unclassified.
†Two hospitalisations for Sicca syndrome were removed from diseases of the musculoskeletal system and connective tissue for comparability.