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. 2018 Feb 8;4(1):e000628. doi: 10.1136/rmdopen-2017-000628

Figure 3.

Figure 3

The genomic region spanning rs4265380 shows enhancer activity. The reporter activity of rs4265380 compared with minimal promoter construct (minP) and normalised to Renilla internal control was measured by luciferase assays on HEK293T (n=3). The values of relative luciferase activity are expressed as mean±SEM. (P=0.0005, Student’s t-test). AS, ankylosing spondylitis.