Table 3.
Data set | No. of fitted measurements* |
No. of estimated net free fluxes, exchange fluxes, G-values |
No. of redundant measurements** |
Maximum acceptable SSR*** |
SSR (contribution to SSR in COMPLETE- MFA) |
---|---|---|---|---|---|
[1,2]Glc | 66 | 8, 5, 10 | 43 | 63 | 11 (45) |
[2,3]Glc | 66 | 10, 3, 10 | 43 | 63 | 8 (47) |
[4,5,6]Glc | 67 | 7, 4, 10 | 46 | 67 | 32 (85) |
[2,3,4,5,6]Glc | 67 | 9, 5, 10 | 43 | 63 | 31 (71) |
[1]+[4,5,6]Glc (1:1) | 66 | 7, 4, 9 | 46 | 67 | 11 (35) |
[1]+[U]Glc (1:1) | 67 | 7, 5, 9 | 46 | 67 | 10 (30) |
[1]+[U]Glc (4:1) | 67 | 7, 6, 9 | 45 | 65 | 33 (61) |
[U]Glc (20%) | 67 | 5, 5, 9 | 48 | 69 | 54 (77) |
[1]Glc | 56 | 7, 6, 8 | 35 | 53 | 6 (54) |
[2]Glc | 53 | 9, 4, 10 | 30 | 47 | 8 (30) |
[3]Glc | 51 | 4, 5, 5 | 37 | 56 | 5 (23) |
[4]Glc | 42 | 2, 2, 0 | 38 | 57 | 15 (20) |
[5]Glc | 51 | 10, 5, 10 | 26 | 42 | 14 (53) |
[6]Glc | 53 | 7, 2, 8 | 36 | 54 | 13 (58) |
COMPLETE-MFA | 813 | 10, 9, 129 | 665 | 738 | 690 |
Number of fitted measurements includes mass isotopomers that were non-zero after correction for natural isotope abundances and external flux constraints (i.e. glucose and acetate).
The number of redundant measurements equals the number of fitted measurements minus the number of estimated parameters, i.e. net free fluxes, exchange fluxes, and G-values.
Maximum acceptable SSR value at 95% confidence level