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Summary of major clinical trials.
| Study | Microvascular | Macrovascular | Mortality |
|---|---|---|---|
| UKPDS (Type 2) | Decreased * | Decreased * | Decreased * |
| DCCT/EDIC (Type 1) | Decreased * | Decreased * | Equivocal * |
| ACCORD (Type 2) | Unclear | - | Increased |
| ADVANCE (Type 2) | Decreased | - | - |
| VADT (Type 2) | Decreased | - | - |
* = Long-term outcome.
