Table 1.
Estimates of cell numbers and ratios in the cynomolgus monkey spinal cord
| Isotropic Fractionator (IF) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Segment | Cell # ±SD million | range million | nN % | neuron % | nNNR ± SD | segment comparison | p-value | significant? | |
| Cervical (c) | 82.7 ± 18.2 | 68–103 | 74.3 | 25.7 | 3.0 ± 0.75 | c. vs th. | 0.26 | n.s. | |
| Thoracic (th) | 118.0 ± 6.2 | 111–120 | 78.5 | 21.5 | 3.7 ± 0.42 | c. vs lu. | 0.75 | n.s. | |
| Lumbar (lu) | 74.3 ±42.6 | 42–122 | 71.8 | 28.2 | 2.8 ± 0.92 | c. vs th.+ lu. | 0.71 | n.s. | |
|
| |||||||||
| Total | 275 ±55.5 | 230–337 | 74.9 | 25.1 | 3.2 ± 0.47 | ||||
|
| |||||||||
| Stereology | |||||||||
| Segment | Cell # ± SD million | range million | glia % | neuron % | endo % | GNR ± SD | segment comparison | p-value | significant? |
|
| |||||||||
| Cervical (c) | 67.6 ± 15.6 | 49–78 | 66.9 | 10.4 | 22.6 | 7.3 ± 3.61 | c. vs th. | 0.41 | n.s. |
| Thoracic (th) | 89.7 ± 10.9 | 83–102 | 68.4 | 12.9 | 18.7 | 5.3 ± 0.85 | c. vs lu. | 0.25 | n.s. |
| Lumbar (lu) | 48.9 ± 7.9 | 40–54 | 61.3 | 16.7 | 22.0 | 4.2 ± 1.95 | c vs th.+lu. | 0.16 | n.s. |
|
| |||||||||
| Total | 206.2 ± 31.2 | 172–334 | 65.5 | 13.3 | 21.1 | 5.6 ± 1.57 | |||
Abbreviations: c, cervical; endo, endothelial cell; GNR, glia-neuron ratio; lu, lumbar; nN, non-neuronal cell; nNNR, non-neuron to neuron ratio; n.s., not significant; SD, standard deviation; th, thoracic.