Table 3.
Characteristics of metabolic parameters in the FBM pigs.
| FBM pig | |||
|
| |||
| Obesogenic diet | Ad libitum: 2.0% cholesterol, 22% fat (lard), 18% fructose | ||
| Control diet | No control diet | ||
| W(−3) | W18 | W30 | |
| (n = 38) | |||
|
| |||
| Duration | 33 weeks | ||
| 12 weeks | |||
| Weight (kg) | 25.6 | 87 | 112∗ |
| Fasting glucose (mmol/L) | 3.9 (3.7–4.2) | 4.1∗ (3.9–4.3) | |
| Fasting insulin (mU/L) | 2.6 (2.2–3.2) | 3.1∗ (2.5–4.4) | |
| HOMA-IR | 0.46 (0.36–0.58) | 0.57∗ (0.43–0.86) | |
| Insulin AUC (mU/L × min) | 862 (671–1048) | 1189∗ (915–1463) | |
| Glucose AUC (mmol/L × min) | 862 (±15) | 948 (±17)∗ | |
| Systolic blood pressure (mmHg) | 141 (127–150) | 131∗ (113–141) | |
| Diastolic blood pressure (mmHg) | 68 (±13) | 66 (±14) | |
| Mean blood pressure (mmHg) | 93 (86–101) | 91 (73–97) | |
| Triglycerides (mmol/L) | 0.4 (0.4–0.5) | 0.5∗ (0.4–0.8) | |
| Cholesterol | |||
| Total (mmol/L) | 4.1 (±0.3) | 16 (±1.1)∗ | |
| HDL (mmol/L) | 0.7 (±0.1) | 2.6 (±0.3)∗ | |
| LDL (mmol/L) | 3.1 (2.4–3.8) | 14∗ (11–15) | |
| LDL/HDL ratio | 3.9 (2.8–5.7) | 5.4∗ (3.6–7.5) | |
For detailed statistical information, see supplementary information. Data is presented as mean (±SD) or median (interquartile range) where appropriate; ∗ p < 0.05.