(a) Univariate analysis of factors that were associated with medications and blood work adherence. (1 = reference)

Variables	Univaried
	Immunomodulators			5-ASA			Biologics			Blood work
	odd	95% CI	p value	odd	95% CI	p value	odd	95% CI	p value	odd	95% CI	p value
Age
Year	1.01	0.91, 1.11	0.83	1.04	0.91, 1.18	0.56	0.95	0.85, 1.06	0.37	1.09	1.00, 1,17	0.04
Sex
Female	1			1			1			1
Male	1.03	0.42, 2.51	0.95	0.8	0.29, 2.29	0.69	0.4	0.08, 1.65	0.19	1.1	0.64, 2.04	0.66
Disease type
Crohn's	1			1			1			1
Ulcerative colitis	1.02	0.43, 2.41	0.96	0.8	0.23, 2.55	0.67	1.1	0.30, 4.07	0.89	1.1	0.58, 1.95	0.84
Duration of disease
Each year diagnosed	0.83	0.71, 0.97	0.02	0.9	0.76, 1.14	0.52	1	0.88, 1.17	0.81	0.8	0.73, 0.96	0.01
Disease severity
Mild	1			1			1			1
Moderate	1.07	0.44, 2.62	0.88	3.2	1.04, 9.88	0.04	1.1	0.28, 4.03	0.93	1.2	0.64, 2.34	0.54
Severe	1.12	0.39, 3.26	0.83	2.6	0.49, 13.6	0.26	1.6	0.23, 11.5	0.62	0.8	0.32, 1.99	0.63
Exacerbation
No	1			1			1			1
Yes	0.94	0.46, 1.94	0.88	0.7	0.22, 2.21	0.53	1.1	0.24, 4.63	0.94	2	1.08, 3.59	0.03
Address
Rural	1			1			1
Urban	1.09	0.49, 2.42	0.84	3.5	1.18, 10.56	0.02	0.5	0.13, 1.91	0.32	1.6	0.87, 3.40	0.125
Clinic visits per year
0 (0-1 visit)	1			1			1			1
1 (2-3 visits)	0.84	0.41, 1.56	0.58	1.2	0.32, 4.26	0.82	2.9	0.27, 3.16	0.38	1.13	0.58, 2.24	0.71
2 (>3 visits)	0.95	0.55, 1.63	0.39	1.1	0.30, 4.33	0.85	0.5	0.12, 2.06	0.34	1.30	0.70, 2.45	0.05